Queen's Genetically

Engineered Machine Team

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2017 Project

Nonribosomal Peptide Synthetases (NRPS)

Indigoidine Tagging

To screen novel synthetic drugs made by NRPS, we need a compatible biomarker. Enter: Indigoidine (blue pigment) and the IndC module.

Substrate Specificity

To engineer our own NRPS system that can integrate amino acids of our choosing, we will explore altering the adenylation domain of NRPS modules.

Tailoring Domains

What if we could expand our novel NRPS drug library by further modifying individual amino acids with functional groups? Here's how we can...

Project Advisors

Queen's iGEM 2017

Dr. John Allingham

Principal Advisor

Dr. Peter Davies

Wet Lab Advisor

Dr. Robert Campbell

Dry Lab Advisor

Graeme Baker

NRPS Advisor

Jacqueline Hellinga

Ross Lab Advisor

Tyler Vance

QGEM Alumna

Dr.Corey Stevens

QGEM Alumna

Dragos Chirac

QGEM Alumna

Contact Us

Email us at info@qgemteam.com, follow us on Facebook (QGEM) or Twitter (@iGEMQueens) or shoot us a message below!